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Identification of murine B cell lines that undergo somatic hypermutation focused to A:T and G:C residues
Activation-induced deaminase (AID) is the master regulator of class switch recombination (CSR) and somatic hypermutation (SHM), but the mechanisms regulating AID function are obscure. The differential pattern of switch plasmid activity in three IgM(+)/AID(+) and two IgG(+)/AID(+) B cell lines prompt...
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| Veröffentlicht in: | Eur J Immunol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979537/ https://ncbi.nlm.nih.gov/pubmed/18081040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737664 |
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