Loss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B1 B cells

A common feature of B cell chronic lymphocytic leukemia (CLL) is chromosomal loss of 13q14, containing the miR15a/16-1 locus controlling B cell proliferation. However, CLL etiology remains unclear. CLL is an adult leukemia with an incidence that increases with advancing age. A unique feature of CLL...

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Foilsithe in:Leukemia
Main Authors: Hayakawa, Kyoko, Formica, Anthony M., Colombo, Matthew J., Shinton, Susan A., Brill-Dashoff, Joni, Morse, Herbert C., Li, Yue-Sheng, Hardy, Richard R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979312/
https://ncbi.nlm.nih.gov/pubmed/27055869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.61
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