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Natural Anti-Intestinal Goblet Cell Autoantibody Production from Marginal Zone B Cells

Expression of a germline V(H)3609/D/J(H)2 IgH in mice results in the generation of B1 B cells with anti-thymocyte/Thy-1 glycoprotein autoreactivity by coexpression of V(k)21-5/J(k)2 L chain leading to production of serum IgM natural autoantibody. In these same mice, the marginal zone (MZ) B cell sub...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Ichikawa, Daiju, Asano, Masanao, Shinton, Susan A., Brill-Dashoff, Joni, Formica, Anthony M., Velcich, Anna, Hardy, Richard R., Hayakawa, Kyoko
Formato: Artigo
Idioma:Inglês
Publicado: AAI 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282382/
https://ncbi.nlm.nih.gov/pubmed/25480561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402383
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