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Loss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B1 B cells
A common feature of B cell chronic lymphocytic leukemia (CLL) is chromosomal loss of 13q14, containing the miR15a/16-1 locus controlling B cell proliferation. However, CLL etiology remains unclear. CLL is an adult leukemia with an incidence that increases with advancing age. A unique feature of CLL...
Sparad:
I publikationen: | Leukemia |
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Huvudupphovsmän: | , , , , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2016
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979312/ https://ncbi.nlm.nih.gov/pubmed/27055869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.61 |
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