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Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation
The Lin28b(+)Let7(−) axis in fetal/neonatal development plays a role in promoting CD5(+) B1a cell generation as a B-1 B cell developmental outcome. Here we identify the Let7 target, Arid3a, as a crucial molecular effector of the B-1 cell developmental program. Arid3a expression is increased at pro-B...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428705/ https://ncbi.nlm.nih.gov/pubmed/30930899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00457 |
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