Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I

Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis. In breast cancer, non-canonical Wnt signaling by Wnt5a has been reported to antagonize tumor growth. He...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Genet
Κύριοι συγγραφείς: Dass, Randall A., Sarshad, Aishe A., Carson, Brittany B., Feenstra, Jennifer M., Kaur, Amanpreet, Obrdlik, Ales, Parks, Matthew M., Prakash, Varsha, Love, Damon K., Pietras, Kristian, Serra, Rosa, Blanchard, Scott C., Percipalle, Piergiorgio, Brown, Anthony M. C., Vincent, C. Theresa
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976976/
https://ncbi.nlm.nih.gov/pubmed/27500936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006217
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