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The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation

In mammals actin contributes to transcription elongation by facilitating establishment of permissive chromatin. Here we report that the F-actin severing protein cofilin-1 is part of the same complex with actin and phosphorylated RNA polymerase (pol) II. In chromatin immunoprecipitation assays cofili...

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Autori principali: Obrdlik, Ales, Percipalle, Piergiorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104811/
https://ncbi.nlm.nih.gov/pubmed/21647301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.1.14508
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