Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I

Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis. In breast cancer, non-canonical Wnt signaling by Wnt5a has been reported to antagonize tumor growth. He...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Dass, Randall A., Sarshad, Aishe A., Carson, Brittany B., Feenstra, Jennifer M., Kaur, Amanpreet, Obrdlik, Ales, Parks, Matthew M., Prakash, Varsha, Love, Damon K., Pietras, Kristian, Serra, Rosa, Blanchard, Scott C., Percipalle, Piergiorgio, Brown, Anthony M. C., Vincent, C. Theresa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976976/
https://ncbi.nlm.nih.gov/pubmed/27500936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006217
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