Загрузка...

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

A potential strategy to alleviate the aggregation of intrinsically disordered proteins (IDPs) is to maintain the native functional state of the protein by small molecule binding. However, the targeting of the native state of IDPs by small molecules has been challenging due to their heterogeneous con...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Curr Alzheimer Res
Главные авторы: Pickhardt, Marcus, Neumann, Thomas, Schwizer, Daniel, Callaway, Kari, Vendruscolo, Michele, Schenk, Dale, St. George-Hyslop, Peter, Mandelkow, Eva M., Dobson, Christopher M., McConlogue, Lisa, Mandelkow, Eckhard, Tóth, Gergely
Формат: Artigo
Язык:Inglês
Опубликовано: Bentham Science Publishers 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976804/
https://ncbi.nlm.nih.gov/pubmed/26510979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/156720501209151019104951
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!