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ApoE: In vitro studies of a small molecule effector
Apolipoprotein E4 (apoE4), one of three isoforms of apoE, is the major risk factor for developing late onset Alzheimer’s disease. The only differences between these isoforms (apoE2, apoE3 and apoE4) are single amino acid changes. Yet these proteins are functionally very different. One approach to am...
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Publicado no: | Biochemistry |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976638/ https://ncbi.nlm.nih.gov/pubmed/27065061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00324 |
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