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ApoE: In vitro studies of a small molecule effector

Apolipoprotein E4 (apoE4), one of three isoforms of apoE, is the major risk factor for developing late onset Alzheimer’s disease. The only differences between these isoforms (apoE2, apoE3 and apoE4) are single amino acid changes. Yet these proteins are functionally very different. One approach to am...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Mondal, Tridib, Wang, Hanliu, DeKoster, Gregory T., Baban, Berevan, Gross, Michael L., Frieden, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976638/
https://ncbi.nlm.nih.gov/pubmed/27065061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00324
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