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Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR

The apolipoprotein E family contains three major isoforms (ApoE4, E3, and E2) that are directly involved with lipoprotein metabolism and cholesterol transport. ApoE3 and apoE4 differ in only a single amino acid with an arginine in apoE4 changed to a cysteine at position 112 in apoE3. Yet only apoE4...

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Detalhes bibliográficos
Main Authors: Garai, Kanchan, Mustafi, Sourajit M, Baban, Berevan, Frieden, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817840/
https://ncbi.nlm.nih.gov/pubmed/19904741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.283
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