Disruption of the CD4-p56lck complex is required for rapid internalization of CD4.

CD4 is a cell surface glycoprotein expressed by a subset of T lymphocytes and functions to enhance T-cell activation. CD4 is noncovalently associated via the cytoplasmic domain with the protein-tyrosine kinase p56lck, a member of the src protein-tyrosine kinase family. Upon activation of protein kin...

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Bibliografske podrobnosti
Main Authors: Sleckman, B P, Shin, J, Igras, V E, Collins, T L, Strominger, J L, Burakoff, S J
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49751/
https://ncbi.nlm.nih.gov/pubmed/1502168
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