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Structural features of the cytoplasmic region of CD4 required for internalization.

CD4, the T cell surface antigen, is phosphorylated and internalized when T cells are activated or treated with a phorbol ester, PMA. The actual phosphorylation sites have been identified and the role of phosphorylation of each on CD4 internalization investigated. Seven different mutants, in each of...

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Detalhes bibliográficos
Main Authors: Shin, J, Doyle, C, Yang, Z, Kappes, D, Strominger, J L
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551683/
https://ncbi.nlm.nih.gov/pubmed/2105883
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