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Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

Two functions have been attributed to the product of the human immunodeficiency virus type 1 vpu open reading frame: it increases virion release from infected cells and induces rapid degradation of CD4 shortly after its synthesis. In the absence of Vpu, newly synthesized gp160 and CD4 associate in t...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Lenburg, M E, Landau, N R
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1993
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7238-7245.1993
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