Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.
Two functions have been attributed to the product of the human immunodeficiency virus type 1 vpu open reading frame: it increases virion release from infected cells and induces rapid degradation of CD4 shortly after its synthesis. In the absence of Vpu, newly synthesized gp160 and CD4 associate in t...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7238-7245.1993 |
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