Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum.

The human immunodeficiency virus type 1 (HIV-1) Vpu protein is a transmembrane phosphoprotein which induces rapid degradation of CD4 in the endoplasmic reticulum (ER). To identify sequences in CD4 for Vpu-induced degradation, we generated four chimeric envelope glycoproteins having the ectodomain of...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Vincent, M J, Raja, N U, Jabbar, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8350411/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5538-5549.1993
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