Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

Degrons are minimal protein features that are sufficient to target proteins for degradation. In most cases, degrons allow recognition by components of the cytosolic ubiquitin proteasome system. Currently, all of the identified degrons only function within the cytosol. Using Saccharomyces cerevisiae,...

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Hlavní autoři:	Rachel Sharninghausen, Jiwon Hwang, Devon D Dennison, Ryan D Baldridge
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2024-11-01
Edice:	eLife
Témata:	degrons protein degradation endoplasmic reticulum associated degradation ERAD
On-line přístup:	https://elifesciences.org/articles/89606
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