The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4.

The nef gene product of human immunodeficiency virus type 1 has been shown to induce CD4 downregulation from the surface of human cells. To determine if this effect is species specific, we used a retroviral vector to transduce the human immunodeficiency virus type 1 nef gene into murine cells expres...

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Main Authors: Garcia, J V, Alfano, J, Miller, A D
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC237521/
https://ncbi.nlm.nih.gov/pubmed/8437228
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