The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef.

Human immunodeficiency virus type 1 Nef down-regulates surface expression of murine and human CD4 but not human CD8. We recently reported that the cytoplasmic domain of CD4 is required for its down-regulation by Nef. Using a chimeric molecule composed of the extracellular and transmembrane domains o...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Anderson, S J, Lenburg, M, Landau, N R, Garcia, J V
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3092-3101.1994
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