Disruption of the CD4-p56lck complex is required for rapid internalization of CD4.

CD4 is a cell surface glycoprotein expressed by a subset of T lymphocytes and functions to enhance T-cell activation. CD4 is noncovalently associated via the cytoplasmic domain with the protein-tyrosine kinase p56lck, a member of the src protein-tyrosine kinase family. Upon activation of protein kin...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sleckman, B P, Shin, J, Igras, V E, Collins, T L, Strominger, J L, Burakoff, S J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7566
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