Disruption of the CD4-p56lck complex is required for rapid internalization of CD4.
CD4 is a cell surface glycoprotein expressed by a subset of T lymphocytes and functions to enhance T-cell activation. CD4 is noncovalently associated via the cytoplasmic domain with the protein-tyrosine kinase p56lck, a member of the src protein-tyrosine kinase family. Upon activation of protein kin...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7566 |
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