An (R)‐Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

Although the range of biocatalysts available for the synthesis of enantiomerically pure chiral amines continues to expand, few existing methods provide access to secondary amines. To address this shortcoming, we have over‐expressed the gene for an (R)‐imine reductase [(R)‐IRED] from Streptomyces sp....

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Bibliografiske detaljer
Udgivet i:ChemCatChem
Main Authors: Hussain, Shahed, Leipold, Friedemann, Man, Henry, Wells, Elizabeth, France, Scott P., Mulholland, Keith R., Grogan, Gideon, Turner, Nicholas J.
Format: Artigo
Sprog:Inglês
Udgivet: WILEY‐VCH Verlag 2015
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973613/
https://ncbi.nlm.nih.gov/pubmed/27547270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cctc.201402797
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