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Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships
Imine reductases (IREDs) have shown great potential as catalysts for the asymmetric synthesis of industrially relevant chiral amines, but a limited understanding of sequence activity relationships makes rational engineering challenging. Here, we describe the characterization of 80 putative and 15 pr...
Shranjeno v:
| izdano v: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244260/ https://ncbi.nlm.nih.gov/pubmed/32494734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9320 |
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