Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway

Liver fibrosis is a serious disease that is characterized by the excess deposition of extracellular matrix (ECM) components. Activated hepatic stellate cells (HSCs) are a major source of ECM and serve as a key regulator in liver fibrogenesis. Inactivation of HSCs is essential for liver fibrotic regr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Chen, Jinling, Xu, Tianhua, Zhu, Dandan, Wang, Jianxin, Huang, Caiqun, Lyu, Lei, Hu, Bin, Sun, Wei, Duan, Yinong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973363/
https://ncbi.nlm.nih.gov/pubmed/27468691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.228
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky