Soluble Egg Antigens of Schistosoma japonicum Induce Senescence of Activated Hepatic Stellate Cells by Activation of the FoxO3a/SKP2/P27 Pathway

BACKGROUND: Liver fibrosis was viewed as a reversible process. The activation of hepatic stellate cells (HSCs) is a key event in the process of liver fibrosis. The induction of senescence of HSCs would accelerate the clearance of the activated HSCs. Previously, we demonstrated that soluble egg antig...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Negl Trop Dis
Egile Nagusiak: Duan, Yinong, Pan, Jing, Chen, Jinling, Zhu, Dandan, Wang, Jianxin, Sun, Xiaolei, Chen, Liuting, Wu, Liting
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5231384/
https://ncbi.nlm.nih.gov/pubmed/28036393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005268
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