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Tankyrase inhibition aggravates kidney injury in the absence of CD2AP
Inappropriate activation of the Wnt/β-catenin pathway has been indicated in podocyte dysfunction and injury, and shown to contribute to the development and progression of nephropathy. Tankyrases, multifunctional poly(ADP-ribose) polymerase (PARP) superfamily members with features of both signaling a...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973355/ https://ncbi.nlm.nih.gov/pubmed/27441654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.217 |
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