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Tankyrase inhibition aggravates kidney injury in the absence of CD2AP

Inappropriate activation of the Wnt/β-catenin pathway has been indicated in podocyte dysfunction and injury, and shown to contribute to the development and progression of nephropathy. Tankyrases, multifunctional poly(ADP-ribose) polymerase (PARP) superfamily members with features of both signaling a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kuusela, S, Wang, H, Wasik, A A, Suleiman, H, Lehtonen, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973355/
https://ncbi.nlm.nih.gov/pubmed/27441654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.217
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