Structure-Based Drug Discovery for Prion Disease Using a Novel Binding Simulation

The accumulation of abnormal prion protein (PrP(Sc)) converted from the normal cellular isoform of PrP (PrP(C)) is assumed to induce pathogenesis in prion diseases. Therefore, drug discovery studies for these diseases have focused on the protein conversion process. We used a structure-based drug dis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ishibashi, Daisuke, Nakagaki, Takehiro, Ishikawa, Takeshi, Atarashi, Ryuichiro, Watanabe, Ken, Cruz, Felipe A., Hamada, Tsuyoshi, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972544/
https://ncbi.nlm.nih.gov/pubmed/27333028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados