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Conformational Properties of Prion Strains Can Be Transmitted to Recombinant Prion Protein Fibrils in Real-Time Quaking-Induced Conversion

The phenomenon of prion strains with distinct biological characteristics has been hypothesized to be involved in the structural diversity of abnormal prion protein (PrP(Sc)). However, the molecular basis of the transmission of strain properties remains poorly understood. Real-time quaking-induced co...

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Bibliografiska uppgifter
Huvudupphovsmän: Sano, Kazunori, Atarashi, Ryuichiro, Ishibashi, Daisuke, Nakagaki, Takehiro, Satoh, Katsuya, Nishida, Noriyuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178718/
https://ncbi.nlm.nih.gov/pubmed/25078700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00585-14
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