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Conformational Properties of Prion Strains Can Be Transmitted to Recombinant Prion Protein Fibrils in Real-Time Quaking-Induced Conversion

The phenomenon of prion strains with distinct biological characteristics has been hypothesized to be involved in the structural diversity of abnormal prion protein (PrP(Sc)). However, the molecular basis of the transmission of strain properties remains poorly understood. Real-time quaking-induced co...

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Detalhes bibliográficos
Main Authors: Sano, Kazunori, Atarashi, Ryuichiro, Ishibashi, Daisuke, Nakagaki, Takehiro, Satoh, Katsuya, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178718/
https://ncbi.nlm.nih.gov/pubmed/25078700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00585-14
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