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Structural conservation of prion strain specificities in recombinant prion protein fibrils in real-time quaking-induced conversion

A major unsolved issue of prion biology is the existence of multiple strains with distinct phenotypes and this strain phenomenon is postulated to be associated with the conformational diversity of the abnormal prion protein (PrP(Sc)). Real-time quaking-induced conversion (RT-QUIC) assay that uses Es...

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Bibliografiske detaljer
Udgivet i:Prion
Main Authors: Sano, Kazunori, Atarashi, Ryuichiro, Nishida, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601500/
https://ncbi.nlm.nih.gov/pubmed/26284507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1062201
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