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Protective role of MyD88-independent innate immune responses against prion infection

Despite recent progress in the understanding of prion diseases, little is known about the host-defense mechanisms against prion. Although it has long been thought that type I interferon (IFN-I) has no protective effect on prion infection, certain key molecules in innate immunity such as toll-like re...

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Detalhes bibliográficos
Main Authors: Ishibashi, Daisuke, Atarashi, Ryuichiro, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510862/
https://ncbi.nlm.nih.gov/pubmed/23093799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22579
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