Protective Role of Interferon Regulatory Factor 3-Mediated Signaling against Prion Infection

Abnormal prion protein (PrP(Sc)) generated from the cellular isoform of PrP (PrP(C)) is assumed to be the main or sole component of the pathogen, called prion, of transmissible spongiform encephalopathies (TSE). Because PrP is a host-encoded protein, acquired immune responses are not induced in TSE....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ishibashi, Daisuke, Atarashi, Ryuichiro, Fuse, Takayuki, Nakagaki, Takehiro, Yamaguchi, Naohiro, Satoh, Katsuya, Honda, Kenya, Nishida, Noriyuki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2012
Θέματα:
Prions
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347345/
https://ncbi.nlm.nih.gov/pubmed/22379081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06326-11
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