Protective Role of Interferon Regulatory Factor 3-Mediated Signaling against Prion Infection

Abnormal prion protein (PrP(Sc)) generated from the cellular isoform of PrP (PrP(C)) is assumed to be the main or sole component of the pathogen, called prion, of transmissible spongiform encephalopathies (TSE). Because PrP is a host-encoded protein, acquired immune responses are not induced in TSE....

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Detalhes bibliográficos
Main Authors: Ishibashi, Daisuke, Atarashi, Ryuichiro, Fuse, Takayuki, Nakagaki, Takehiro, Yamaguchi, Naohiro, Satoh, Katsuya, Honda, Kenya, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Prions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347345/
https://ncbi.nlm.nih.gov/pubmed/22379081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06326-11
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