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Protective Role of Interferon Regulatory Factor 3-Mediated Signaling against Prion Infection
Abnormal prion protein (PrP(Sc)) generated from the cellular isoform of PrP (PrP(C)) is assumed to be the main or sole component of the pathogen, called prion, of transmissible spongiform encephalopathies (TSE). Because PrP is a host-encoded protein, acquired immune responses are not induced in TSE....
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347345/ https://ncbi.nlm.nih.gov/pubmed/22379081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06326-11 |
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