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MyD88: a central player in innate immune signaling

MyD88 is the canonical adaptor for inflammatory signaling pathways downstream of members of the Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor families. MyD88 links IL-1 receptor (IL-1R) or TLR family members to IL-1R-associated kinase (IRAK) family kinases via homotypic protein-protein...

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Bibliographic Details
Published in:F1000Prime Rep
Main Authors: Deguine, Jacques, Barton, Gregory M.
Format: Artigo
Language:Inglês
Published: Faculty of 1000 Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229726/
https://ncbi.nlm.nih.gov/pubmed/25580251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P6-97
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