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Tumor responsiveness to statins requires overexpression of the ARF6 pathway

The mevalonate pathway results in the prenylation of small GTPases, which are pivotal for oncogenesis and cancer malignancies. However, inhibitors of this pathway, such as statins, have not necessarily produced favorable results in clinical trials. We recently identified properties of statin respond...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Oncol
Egile Nagusiak: Sabe, Hisataka, Hashimoto, Ari, Hashimoto, Shigeru, Oikawa, Tsukasa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972113/
https://ncbi.nlm.nih.gov/pubmed/27652329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1185564
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