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Tumor responsiveness to statins requires overexpression of the ARF6 pathway
The mevalonate pathway results in the prenylation of small GTPases, which are pivotal for oncogenesis and cancer malignancies. However, inhibitors of this pathway, such as statins, have not necessarily produced favorable results in clinical trials. We recently identified properties of statin respond...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972113/ https://ncbi.nlm.nih.gov/pubmed/27652329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1185564 |
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