The EGFR-GEP100-Arf6 pathway in breast cancer: Full invasiveness is not from the inside

Arf6 and its effector AMAP1 are overexpressed in malignant breast cancer cells, and are involved in their invasion and metastasis. We recently revealed that GEP100, a guanine nucleotide exchanging factor, is responsible for the activation of Arf6 which induces invasion and metastasis. GEP100 associa...

Full description

Saved in:
Bibliographic Details
Main Authors: Sabe, Hisataka, Hashimoto, Shigeru, Morishige, Masaki, Hashimoto, Ari, Ogawa, Eiji
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2008
Subjects:
Commentary & View
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634987/
https://ncbi.nlm.nih.gov/pubmed/19262097
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items