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Bispecific anti-HIV-1 antibodies with enhanced breadth and potency
Broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoprotein (Env) suppress viremia in animal models of HIV-1 and humans. To achieve potent activity without the emergence of viral escape mutants, co-administration of different bNAbs is necessary to target distinct epitopes essenti...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4970321/ https://ncbi.nlm.nih.gov/pubmed/27315478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.050 |
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