Bispecific anti-HIV-1 antibodies with enhanced breadth and potency

Broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoprotein (Env) suppress viremia in animal models of HIV-1 and humans. To achieve potent activity without the emergence of viral escape mutants, co-administration of different bNAbs is necessary to target distinct epitopes essenti...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Bournazos, Stylianos, Gazumyan, Anna, Seaman, Michael S., Nussenzweig, Michel C., Ravetch, Jeffrey V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970321/
https://ncbi.nlm.nih.gov/pubmed/27315478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.050
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk