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Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity
Broadly neutralizing antibodies (bNAbs) against HIV-1 provide both effective pre-exposure prophylaxis and treatment of HIV-1 infection in murine and non-human primate models, suggesting their potential use in humans. While much is known about the role of variable domains in the neutralization breadt...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167398/ https://ncbi.nlm.nih.gov/pubmed/25215485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.023 |
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