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Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection
In vivo protection by antimicrobial neutralizing Abs can require the contribution of effector functions mediated by Fc-Fcγ receptor (Fc-FcγR) interactions for optimal efficacy. In influenza, broadly neutralizing anti-hemagglutinin (anti-HA) stalk mAbs require Fc-FcγR interactions to mediate in vivo...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731186/ https://ncbi.nlm.nih.gov/pubmed/26731473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84428 |
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