Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis

Podocytes are terminally differentiated glomerular epithelial cells. Podocyte loss has been found in many renal diseases. Cdk5 is a cyclin-dependent protein kinase which is predominantly regulated by p35. To study the role of Cdk5/p35 in podocyte survival, we first applied western blotting (WB) anal...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Zheng, Ya-Li, Zhang, Xia, Fu, Hai-Xia, Guo, Mei, Shukla, Varsha, Amin, Niranjana D., E, Jing, Bao, Li, Luo, Hong-Yan, Li, Bo, Lu, Xiao-Hua, Gao, Yong-Cai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968817/
https://ncbi.nlm.nih.gov/pubmed/27479491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160252
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