Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma

Deficiency of methylthioadenosine phosphorylase (MTAP) supports melanoma development and progression through accumulation of its substrate 5’-methylthioadenosine (MTA), which leads amongst others to a constitutive inhibition of protein arginine methyltransferases (PRMTs) and activation of the transc...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Limm, Katharina, Dettmer, Katja, Reinders, Jörg, Oefner, Peter J., Bosserhoff, Anja-Katrin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968798/
https://ncbi.nlm.nih.gov/pubmed/27479139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160348
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items