Expression and Function of Methylthioadenosine Phosphorylase in Chronic Liver Disease

To study expression and function of methylthioadenosine phosphorylase (MTAP), the rate-limiting enzyme in the methionine and adenine salvage pathway, in chronic liver disease. DESIGN: MTAP expression was analyzed by qRT-PCR, Western blot and immunohistochemical analysis. Levels of MTA were determine...

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Autori principali: Czech, Barbara, Dettmer, Katja, Valletta, Daniela, Saugspier, Michael, Koch, Andreas, Stevens, Axel P., Thasler, Wolfgang E., Müller, Martina, Oefner, Peter J., Bosserhoff, Anja-Katrin, Hellerbrand, Claus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855635/
https://ncbi.nlm.nih.gov/pubmed/24324622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080703
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