Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates

The genomes of large numbers of single cells must be sequenced to further understanding of the biological significance of genomic heterogeneity in complex systems. Whole genome amplification (WGA) of single cells is generally the first step in such studies, but is prone to nonuniformity that can com...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Leung, Kaston, Klaus, Anders, Lin, Bill K., Laks, Emma, Biele, Justina, Lai, Daniel, Bashashati, Ali, Huang, Yi-Fei, Aniba, Radhouane, Moksa, Michelle, Steif, Adi, Mes-Masson, Anne-Marie, Hirst, Martin, Shah, Sohrab P., Aparicio, Samuel, Hansen, Carl L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968760/
https://ncbi.nlm.nih.gov/pubmed/27412862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520964113
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