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Recruitment of Light Chains by Homologous and Heterologous Fibrils Shows Distinctive Kinetic and Conformational Specificity
Light chain amyloidosis is a protein misfolding disease in which immunoglobulin light chains aggregate as insoluble fibrils that accumulate in extracellular deposits. Amyloid fibril formation in vitro has been described as a nucleation–polymerization, autocatalytic reaction in which nascent fibrils...
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| Vydáno v: | Biochemistry |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968207/ https://ncbi.nlm.nih.gov/pubmed/27158939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00090 |
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