Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

Therapeutic antibodies continue to develop as an emerging drug class, with a need for preclinical tools to better predict in vivo characteristics. Transgenic mice expressing human neonatal Fc receptor (hFcRn) have potential as a preclinical pharmacokinetic (PK) model to project human PK of monoclona...

全面介紹

Na minha lista:
書目詳細資料
發表在:MAbs
Main Authors: Avery, Lindsay B., Wang, Mengmeng, Kavosi, Mania S., Joyce, Alison, Kurz, Jeffrey C., Fan, Yao-Yun, Dowty, Martin E., Zhang, Minlei, Zhang, Yiqun, Cheng, Aili, Hua, Fei, Jones, Hannah M., Neubert, Hendrik, Polzer, Robert J., O'Hara, Denise M.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
主題:
Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968115/
https://ncbi.nlm.nih.gov/pubmed/27232760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1193660
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍