CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications

Bispecific immunoglobulins (Igs) typically contain at least two distinct variable domains (Fv) that bind to two different target proteins. They are conceived to facilitate clinical development of biotherapeutic agents for diseases where improved clinical outcome is obtained or expected by combinatio...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Steinmetz, Anke, Vallée, François, Beil, Christian, Lange, Christian, Baurin, Nicolas, Beninga, Jochen, Capdevila, Cécile, Corvey, Carsten, Dupuy, Alain, Ferrari, Paul, Rak, Alexey, Wonerow, Peter, Kruip, Jochen, Mikol, Vincent, Rao, Ercole
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968095/
https://ncbi.nlm.nih.gov/pubmed/26984268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1162932
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