Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins

Panton–Valentine leukocidin (PVL) is a pore-forming toxin associated with current outbreaks of community-associated methicillin-resistant strains and implicated directly in the pathophysiology of Staphylococcus aureus-related diseases. Humanized heavy chain-only antibodies (HCAb) were generated agai...

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Bibliografiske detaljer
Main Authors: Laventie, Benoît-Joseph, Rademaker, Hendrik Jan, Saleh, Maher, de Boer, Ernie, Janssens, Rick, Bourcier, Tristan, Subilia, Audrey, Marcellin, Luc, van Haperen, Rien, Lebbink, Joyce H. G., Chen, Tao, Prévost, Gilles, Grosveld, Frank, Drabek, Dubravka
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182740/
https://ncbi.nlm.nih.gov/pubmed/21930905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102265108
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