Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins

Panton–Valentine leukocidin (PVL) is a pore-forming toxin associated with current outbreaks of community-associated methicillin-resistant strains and implicated directly in the pathophysiology of Staphylococcus aureus-related diseases. Humanized heavy chain-only antibodies (HCAb) were generated agai...

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Detalhes bibliográficos
Main Authors: Laventie, Benoît-Joseph, Rademaker, Hendrik Jan, Saleh, Maher, de Boer, Ernie, Janssens, Rick, Bourcier, Tristan, Subilia, Audrey, Marcellin, Luc, van Haperen, Rien, Lebbink, Joyce H. G., Chen, Tao, Prévost, Gilles, Grosveld, Frank, Drabek, Dubravka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182740/
https://ncbi.nlm.nih.gov/pubmed/21930905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102265108
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