Daptomycin versus Vancomycin in a Methicillin-Resistant Staphylococcus aureus Endophthalmitis Rabbit Model: Bactericidal Effect, Safety, and Ocular Pharmacokinetics

Staphylococcus aureus is a frequent cause of acute endophthalmitis, and infection with this virulent bacterium is often associated with a poor visual outcome. In this study, we investigated the bactericidal efficacy and the safety of intravitreal daptomycin (DAP), a lipopeptide antibiotic with broad...

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Detalhes bibliográficos
Main Authors: Lefèvre, Sophie, Saleh, Maher, Marcellin, Luc, Subilia, Audrey, Bourcier, Tristan, Prévost, Gilles, Jehl, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346597/
https://ncbi.nlm.nih.gov/pubmed/22371888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05745-11
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